A Generalized Kruskal–Wallis Test Incorporating Group Uncertainty with Application to Genetic Association Studies
نویسندگان
چکیده
منابع مشابه
Permutation-based variance component test in generalized linear mixed model with application to multilocus genetic association study
BACKGROUND In many medical studies the likelihood ratio test (LRT) has been widely applied to examine whether the random effects variance component is zero within the mixed effects models framework; whereas little work about likelihood-ratio based variance component test has been done in the generalized linear mixed models (GLMM), where the response is discrete and the log-likelihood cannot be ...
متن کاملa new type-ii fuzzy logic based controller for non-linear dynamical systems with application to 3-psp parallel robot
abstract type-ii fuzzy logic has shown its superiority over traditional fuzzy logic when dealing with uncertainty. type-ii fuzzy logic controllers are however newer and more promising approaches that have been recently applied to various fields due to their significant contribution especially when the noise (as an important instance of uncertainty) emerges. during the design of type- i fuz...
15 صفحه اولA powerful and robust test in genetic association studies.
There are several well-known single SNP tests presented in the literature for detecting gene-disease association signals. Having in place an efficient and robust testing process across all genetic models would allow a more comprehensive approach to analysis. Although some studies have shown that it is possible to construct such a test when the variants are common and the genetic model satisfies...
متن کاملA novel copy number variants kernel association test with application to autism spectrum disorders studies
MOTIVATION Copy number variants (CNVs) have been implicated in a variety of neurodevelopmental disorders, including autism spectrum disorders, intellectual disability and schizophrenia. Recent advances in high-throughput genomic technologies have enabled rapid discovery of many genetic variants including CNVs. As a result, there is increasing interest in studying the role of CNVs in the etiolog...
متن کاملBayesian Model Uncertainty and Prior Choice with Applications to Genetic Association Studies
Bayesian Model Uncertainty) Bayesian Model Uncertainty and Prior Choice with Applications to Genetic Association Studies
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biometrics
سال: 2013
ISSN: 0006-341X,1541-0420
DOI: 10.1111/biom.12006